The transcript captures an insightful conversation highlighting Dr. Anthony Fauci’s career and his transition from the National Institutes of Health after over 50 years. Dr. Fauci, recognized as a leading infectious disease expert, has guided the country through multiple health crises including AIDS, Ebola, Zika, and most recently, COVID-19. Despite leaving his role, he insists he is not retiring—rather, entering a new chapter, with plans to remain active and purposeful. Dr. Fauci shares his vitality secrets, attributing his energy to healthy living, purposeful work, and good genetics. Dr. Jennifer Ashton provides an intimate look at his daily routine, revealing his diet, exercise habits, and family life with his wife, Dr. Christine Grady, a key support in maintaining his health during the pandemic. As Dr. Fauci prepares to embrace grandfatherhood and possibly explore social media, he reflects on his upcoming transition and the meaningful years dedicated to public service, leaving a lasting impact not just on the scientific community but also on the public.