ABC’s Dr. Jennifer Ashton profiles Dr. Anthony Fauci as he prepares to leave the NIH after 54 years of service, emphasizing that he sees it as a new chapter rather than retirement. Fauci credits his energy and longevity—he says he feels 40 to 45 at nearly 82—to regular exercise, moderation in food and alcohol, strong family genetics, and, above all, having a meaningful purpose. His wife, Dr. Christine Grady, describes helping him maintain basic self-care during the intense early months of COVID-19 by ensuring he ate, drank water, and slept. Fauci discusses plans to spend more time with family, travel, read, watch sports, and become a grandfather, while remaining open to future ways of communicating with the public.